Vascular disease - clopidogrel and dipyridamole

NICE has recommended that: the combination of MR dipyridamole and aspirin is used as part of the prevention of occlusive vascular events in people who have had an ischaemic stroke or a transient ischaemic attack for a period of 2 years from the most recent event. After this period of time, or if ...

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NICE has recommended that:

• the combination of MR dipyridamole and aspirin is used as part of the prevention of occlusive vascular events in people who have had an ischaemic stroke or a transient ischaemic attack for a period of 2 years from the most recent event. After this period of time, or if MR dipyridamole causes adverse effects, the person should receive standard care which includes long-term treatment with low-dose aspirin
• clopidogrel alone (within its licensed indications) is used as part of prevention of occlusive vascular events in people who are intolerant of low-dose aspirin and either have experienced an occlusive vascular event or have symptomatic peripheral arterial disease.

In these recommendations, NICE has defined aspirin intolerance as either:

• a proven hypersensitivity to aspirin or
• a history of severe indigestion caused by low-dose aspirin.

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