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Sepsis (severe) - drotrecogin

Drotrecogin alpha (activated) for severe sepsis

Guidance type:  Technology appraisal
Date issued:  September 2004

We will consult on our review plans for this guidance in September 2007.

Reference:  TA84

Summary

Drotrecogin alfa (activated) is recommended for adult patients who

  • have severe sepsis that has resulted in multiple organ failure (two or more major organs are not working properly) and
  • are being given the most appropriate intensive care support for their condition.

The use of drotrecogin alfa (activated) should be started and supervised by a specialist consultant with skills in intensive care and experience in the care of patients with sepsis.

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