Thrombocytopenic purpura - romiplostim (TA221)
NICE recommends romiplostim as a possible treatment for some people with chronic ITP (see below). Only a haematologist (a doctor who specialises in diseases of the blood) should start and supervise treatment with romiplostim.
Who can have romiplostim?
You should be able to have romiplostim if:
- your chronic ITP has not improved even though you have tried other available treatments or
- you have severe chronic ITP and a high risk of bleeding that needs frequent courses of treatment.
You can ask your specialist to explain whether romiplostim is appropriate for you.
Why has NICE said this?
NICE looks at how well treatments work, and also at how well they work in relation to how much they cost the NHS. NICE recommended romiplostim for people with chronic ITP who meet the criteria listed above because it works better than other treatments available on the NHS. Although it also costs more than other treatments, this was justified by the benefits it provided.
Romiplostim has a marketing authorisation 'for adult chronic immune (idiopathic) thrombocytopenic purpura (ITP) splenectomised patients who are refractory to other treatments (e.g. corticosteroids, immunoglobulins)'. The marketing authorisation also states that romiplostim 'may be considered as second line treatment for adult non-splenectomised patients where surgery is contra-indicated'. NICE can make recommendations only within a product’s marketing authorisation. The recommendations in section 1 of this guidance are only for people whose condition meets the criteria of the marketing authorisation.
This page was last updated: 22 July 2013
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- TA221 Romiplostim ar gyfer pwrpwra thrombosytopenig imiwnedd cronig (idiopathig): deall canllawiau NICE (fformat MS Word)
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