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Gastric cancer (advanced HER-2 positive) - trastuzumab (herceptin)

Trastuzumab for the treatment of HER2 positive advanced gastric cancer

Status: In progress
Expected date of issue: November 2010
Referral date: March 2009
Wave: 19
Process: STA
Notes:

Cancer reform strategy Batch 5

Topic area:
  • Cancer
  • Digestive system
 

NICE project team

Executive Lead: Andrew Dillon
Technical Lead: Joanne Fielding
Communications manager: TBC
Project manager: Laura Malone
Evidence review group: NHS Centre for Reviews and Dissemination and Centre for Health Economics
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Provisional schedule

Closing date for invited submissions / evidence submission: 1 March 2010
1st appraisal committee meeting: 09 June 2010
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Consultees and Commentators

Consultees Commentators (no right of appeal)

Manufacturers / Sponsors

  • Roche Products (trastuzumab)

 

Patient / Carer Groups

  • Afiya Trust
  • Black Health Agency
  • CANCERactive
  • Cancer Black Care
  • Cancer Equality
  • Chinese National Healthy Living Centre
  • Confederation of Indian Organisations
  • CORE – The Digestive Disorders Foundation
  • Counsel and Care
  • Equalities National Council
  • Helen Rollason Heal Cancer Charity
  • Macmillan Cancer Support
  • Maggie's Centres
  • Marie Curie Cancer Care
  • Muslim Council of Great Britain
  • Muslim Health Network
  • National Cancer Alliance
  • National Council for Palliative Care
  • Oesophageal Patients Association
  • Rarer Cancers Forum
  • S.C.A.N
  • South Asian Health Foundation
  • Specialised Healthcare Alliance
  • Sue Ryder Care
  • Tenovus

 

Professional groups

  • Association of Cancer Physicians
  • British Association for Services to the Elderly
  • British Geriatric Society
  • British Institute of Radiology
  • British Oncological Association
  • British Psychosocial Oncology Society
  • British Society of Gastroenterology
  • Cancer Networks Pharmacists Forum
  • Cancer Research UK
  • Royal College of General Practitioners
  • Royal College of Nursing
  • Royal College of Pathologists
  • Royal College of Physicians, Medical Oncology Joint Special Committee
  • Royal College of Radiologists
  • Royal Pharmaceutical Society
  • Royal Society of Medicine – Intellectual Disabilities Forum
  • Society and College of Radiographers
  • United Kingdom Clinical Pharmacy Association
  • United Kingdom Oncology Nursing Society

 

Others

  • Department of Health
  • Kingston PCT
  • NHS Halton and St.Helens
  • Welsh Assembly Government

General

  • Board of Community Health Councils in Wales
  • British National Formulary
  • Commissioning Support Appraisals Service
  • Department of Health, Social Services and Public Safety for Northern Ireland
  • Medicines and Healthcare products Regulatory Agency
  • National Association of Primary Care
  • National Public Health Service for Wales
  • NHS Alliance
  • NHS Confederation
  • NHS Purchasing and Supply Agency
  • NHS Quality Improvement Scotland
  • Scottish Medicines Consortium

 

Comparator manufacturer(s)

  • Actavis (epirubicin, oxaliplatin)
  • Bristol-Myers Squibb (cisplatin)
  • Cephalon (doxorubicin)
  • Hameln Pharmaceuticals (doxorubicin, epirubicin)
  • Hospira (epirubicin, 5-FU, cisplatin, oxaliplatin, doxorubicin)
  • Medac UK (5-FU, doxorubicin)
  • Mylan (oxaliplatin)
  • Pfizer (epirubicin, cisplatin, doxorubicin)
  • Roche Products (capecitabine)
  • Sanofi-Aventis (docetaxel, oxaliplatin,)
  • Schering-Plough (doxorubicin)
  • Teva UK (cisplatin, doxorubicin, epirubicin, oxaliplatin)
  • Wockhardt (cisplatin, doxorubicin, epirubicin, oxaliplatin, 5-FU)

 

Relevant research groups

  • Institute of Cancer Research
  • MRC Clinical Trials Unit
  • National Cancer Research Institute
  • National Cancer Research Network
  • National Institute for Health Research
  • Policy Research Institute on Ageing and Ethnicity
  • Research Institute of the Care of Older People

 

Evidence Review Group

  • Institute of Cancer Research
  • MRC Clinical Trials Unit
  • National Cancer Research Institute
  • National Cancer Research Network
  • National Institute for Health Research
  • Policy Research Institute on Ageing and Ethnicity
  • Research Institute of the Care of Older People

 

Associated Guideline Groups

  • National Collaborating Centre for Cancer

 

Associated Public Health Groups

  • None

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Project history

Date Update
19 November 2009 Following on from advice received from the manufacturer, this appraisal has been rescheduled to align with latest regulatory expectations. Therefore, we now anticipate that the appraisal will begin during late January 2010. The deadline for submissions is expected in approximately early April 2010.
13 August 2009 Please note that following on from advice received from the manufacturer, this appraisal has been rescheduled to align with latest regulatory expectations. Therefore, we now anticipate that the appraisal will begin during late January 2010. The deadline for submissions is expected in approximately early April 2010.
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Key documents

This page was last updated:   24 December 2009