Navigation

Bowel function - methylnaltrexone [ID2]

Methylnaltrexone for the treatment of opioid-induced bowel dysfunction in advanced illness or palliative care

Status: History
Expected date of issue: November 2013
Referral date: July 2008
Process: STA
Topic area:
  • Digestive system
 

NICE project team

Executive Lead: TBC
Technical Lead: TBC
Communications manager: TBC
Project manager: Jeremy Powell
Top


 

Provisional schedule

Closing date for invited submissions / evidence submission: TBC
1st appraisal committee meeting: TBC
Top


 

Consultees and commentators

 

Consultees

Commentators (no right to submit or appeal)

Manufacturers / Sponsors

  • Wyeth Pharmaceuticals (methylnaltrexone)

Patient / Carer Groups

  • Action on Pain
  • Afiya Trust
  • Age Concern England
  • Black Health Agency
  • Bladder and Bowel Foundation
  • British Ethnic Health Awareness  Foundation (BEHAF)
  • CANCERactive
  • Cancerbackup
  • Cancer Black Care
  • Cancer Equality
  • Cancer Voices
  • Chinese National Healthy Living Centre
  • Confederation of Indian Organisations
  • CORE (Digestive Disorders Foundation)
  • Counsel and Care
  • Equalities National Council
  • Helen Rollason Heal Cancer Charity
  • Help the Aged
  • Help the Hospices
  • Macmillan Cancer Support
  • Maggie?s Centres
  • Marie Curie Cancer Care
  • Motor Neurone Disease Association
  • Muslim Council of Great Britain
  • Muslim Health Network
  • National Cancer Alliance
  • National Council for Palliative Care
  • Pain Concern
  • Pain Relief Foundation
  • South Asian Health Foundation
  • Specialised Healthcare Alliance
  • Sue Ryder Care
  • Tenovus Cancer Information Centre

Professional groups

  • Association for Palliative Medicine
  • Association of Cancer Physicians
  • British Association for Services to the Elderly
  • British Geriatrics Society
  • British Oncological Association (BOA)
  • British Pain Society
  • British Psychosocial Oncology Society (BPOS)
  • Cancer Networks Pharmacists Forum
  • Cancer Research UK
  • Palliative Care Pharmacists Network
  • Royal College of General Practitioners
  • Royal College of Nursing
  • Royal College of Pathologists
  • Royal College of Physicians
  • Royal Pharmaceutical Society
  • Royal Society of Medicine – Intellectual Disabilities Forum
  • United Kingdom Clinical Pharmacy Association
  • United Kingdom Oncology Nursing Society

Others

  • Department of Health
  • Richmond and Twickenham PCT
  • Sunderland Teaching PCT
  • Welsh Assembly Government

General

  • Age Concern Cymru
  • Board of Community Health Councils in Wales
  • British National Formulary
  • Cancer Care Cymru
  • Department of Health, Social Services and Public Safety for Northern Ireland
  • Medicines and Healthcare products Regulatory Agency
  • National Association of Primary Care
  • National Public Health Service for Wales
  • NHS Alliance
  • NHS Confederation
  • NHS Purchasing and Supply Agency
  • NHS Quality Improvement Scotland
  • Scottish Medicines Consortium

Comparator manufacturer(s)

  • Actavis UK (glycerol suppositories)
  • Boehringer Ingelheim (bisacodyl suppositories)
  • E.C. DeWitt (phosphates enema)
  • Essential Generics (arachis oil enema, phosphates enema)
  • Forest Laboratories UK (arachis oil enema, phosphates enema)
  • IVAX Pharmaceuticals UK (glycerol suppositories)
  • Martindale pharma (bisacodyl suppositories, glycerol suppositories)
  • Reckitt Benckiser (Senokot direct relief suppositories)
  • Teva UK (glycerol suppositories)
  • Thornton & Ross (glycerol suppositories)

Relevant research groups

  • Institute of Cancer Research
  • MRC Clinical Trials Unit
  • National Cancer Research Institute
  • National Cancer Research Network
  • National Institute for Health Research
  • Policy Research Institute on Ageing and Ethnicity
  • Research Institute for the Care of Older People
  • United Kingdom Clinical Research Network

Evidence Review Group

  • Liverpool Reviews and Implementation Group, University of Liverpool
  • National Institute for Health Research Health Technology Assessment Programme

Associated Guideline Groups

  • None

Associated Public Health Groups

  • None

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Top


 

Project history

Date Update
23 June 2009 Stakeholders informed that this appraisal is suspended. In order to enable NICE to undertake a robust appraisal the manufacturer will submit in early/mid 2010, by which time results from a number of studies currently ongoing will be available
Top


 

Key documents

This page was last updated: 25 March 2013

Accessibility | Cymraeg | Freedom of information | Vision Impaired | Contact Us | Glossary | Data protection | Copyright | Disclaimer | Terms and conditions

Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.

Selected, reliable information for health and social care in one place

Accessibility | Cymraeg | Freedom of information | Vision Impaired | Contact Us | Glossary | Data protection | Copyright | Disclaimer | Terms and conditions

Copyright 2014 National Institute for Health and Care Excellence. All rights reserved.