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Percutaneous radiofrequency ablation of renal cancer

Guidance issued Guidance issued
 
IP Guidance Number: IPG91
 
Summary:

The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on percutaneous radiofrequency ablation of renal cancer.

Description:

There are few symptoms in the early stages of renal cancer. Typically symptoms develop as the disease progresses. The first symptom is often blood in the urine; pain and flank mass are the other classic symptoms.

The standard treatment for renal cancer is total or partial nephrectomy. However, with the improvement of medical imaging techniques, which have increased the detection of small incidental renal tumours, less invasive procedures have emerged. These include laparoscopic partial nephrectomy, cryoablation, high-intensity ultrasound and radiofrequency ablation.

Percutaneous radiofrequency ablation may be particularly indicated in patients with small renal tumours (for example less than 4cm diameter), in whom surgery may not be well tolerated, or in patients who refuse surgery.

CT scanning or ultrasound is used for image guidance, and the tumour is destroyed by heating to temperatures exceeding 60°C. In RFA, temperature changes are induced using high-frequency alternating current applied via an electrode or electrodes placed within the tissue to generate ionic agitation.

Arrangements:

Other (see guidance)

Topic Area:

Cancer
Urogenital

Specialty:

Clinical oncology
Medical oncology
Urology

Specialist advice has
been sought from:
Date notified to NICE: 03 June 2003
Guidance Publication Date: 22 September 2004
Contact Details:
Project Manager
(for general enquiries or comments)
Ben Doak
Technical Lead
(for procedure specific enquiries or comments)
Sally Wortley
ip@nice.org.uk
Contact Address:

Interventional Procedures Programme
National Institute for Health and Clinical Excellence
MidCity Place
71 High Holborn
London
WC1V 6NA


Links:

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