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Autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy

 
Guidance issued
 
IPG Number: IPG274

Summary

The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy.

This document together with the guidance published on allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus (http://www.nice.org.uk/ipg257guidance) replaces previous guidance on pancreatic islet cell transplantation.

Description

Patients with chronic pancreatitis or some pancreatic tumours may require the surgical removal of all, or part, of their pancreas. As the pancreas is responsible for insulin production, surgical removal of the pancreas causes these patients to develop insulin-dependent diabetes.

Autologous pancreatic islet cell transplantation involves the removal of parts of the patient's own pancreas (the islet cells, which are responsible for insulin production), after the pancreas has been removed. These cells are then inserted into the patient's liver to restart insulin production within the body.

OPCS code:

Details

Arrangement:
Special
Topic area:
Digestive system
Endocrine, nutritional and metabolic
Surgical procedures
Specialty:
Gastroinstestinal surgery
Gastroenterology
Specialist advice has been sought from:
  • British Transplant Society
  • Diabetes UK
  • Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland
  • British Society of Gastroenterology
Date notified to NICE:
29 November 2007
Provisional consultation date:
Summer 2008
Guidance issue date:
24 September 2008

Contact details:

Project manager (for general enquiries or comments)
(for general enquiries or comments)
Technical lead
(for procedure specific enquiries or comments)
Sally Hamilton
Contact Address:

Interventional Procedures Programme
National Institute for Health and Clinical Excellence
MidCity Place
71 High Holborn
London
WC1V 6NA

Links: