Autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy

The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy.

This document together with the guidance published on allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus (http://www.nice.org.uk/ipg257guidance) replaces previous guidance on pancreatic islet cell transplantation.

Patients with chronic pancreatitis or some pancreatic tumours may require the surgical removal of all, or part, of their pancreas. As the pancreas is responsible for insulin production, surgical removal of the pancreas causes these patients to develop insulin-dependent diabetes.

Autologous pancreatic islet cell transplantation involves the removal of parts of the patient's own pancreas (the islet cells, which are responsible for insulin production), after the pancreas has been removed. These cells are then inserted into the patient's liver to restart insulin production within the body.

Other (see guidance)

Digestive system
Endocrine, nutritional and metabolic
Surgical procedures

Gastro-enterology
Gastroinstestinal surgery

British Transplant Society

British Diabetic Association

Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland

British Society of Gastroenterology

Interventional Procedures Programme
National Institute for Health and Clinical Excellence
MidCity Place
71 High Holborn
London
WC1V 6NA