| CG104 |
Metastatic malignant disease of unknown primary origin (CG104) |
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Diagnosis and management of metastatic malignant disease of unknown primary origin
The advice in the NICE guideline covers:
- the treatment and care of adults with suspected or diagnosed cancer of unknown primary, including people who have been treated for cancer before.
In this guideline ‘cancer of unknown primary’ refers to a particular type of cancer, called carcinoma.
It does not specifically look at:
- children (under 18) with cancer of unknown primary
- adults with cancer, or likely to have cancer, that has spread (also called metastatic cancer) with a known site of primary origin
- adults with cancer that is not carcinoma (for example lymphoma, melanoma, sarcoma).
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Other information
- CG104 Metastatic malignant disease of unknown primary origin: NICE guideline (web format)
- CG104 Metastatic malignant disease of unknown primary origin: evidence review
How this guidance was produced
Background information
This page was last updated: 10 January 2012
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Guideline formats
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Implementation tools and resources
- Audit support
- Baseline assessment tool
- Costing statement
- Slide set
- Metastatic malignant disease: online educational tool
See this guidance in practice
Patient
The summary of the key recommendations in the guidance written for patients, carers and those with little medical knowledge and may be used in local patient information leaflets.
Quick Reference Guide
The quick reference guide presents recommendations for health professionals
NICE Guideline
The published NICE clinical guideline, contains the recommendations for health professionals and NHS bodies.
Full Guideline
The published full clinical guideline for specialists with background, evidence, recommendations and methods used.

